Low-Dose Heparin for Severe Sepsis
نویسندگان
چکیده
منابع مشابه
Low-dose, off-label drotrecogin alfa (xigris) in severe sepsis.
OBJECTIVE In this article, we describe a successful low-dose, off-label usage of drotrecogin alfa (Xigris), given at 18 mcg/kg per hour, in a patient with severe sepsis who had an Acute Physiology and Chronic Health Evaluation II (APACHE II) score of 26 and multiorgan failure. PATIENT A 64-year-old man was admitted to the surgical intensive-care unit of Winthrop University Hospital in Mineola...
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The present study aimed to investigate whether low-dose heparin improves the condition of patients suffering from early disseminated intravascular coagulation (pre-DIC) during sepsis. In total, 37 patients were randomly divided into low-dose heparin intervention and control groups. The heparin group received a low-dose of heparin for 5-7 days, while the other group received only saline. The two...
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To assess whether adding low-dose heparin to the infusate of patients receiving parenteral nutrition reduced the incidence of septic complications related to the central venous catheter, 80 consecutive patients requiring intravenous feeding were studied. Half of these patients received heparin 1 unit/ml of infusate, while in the remaining 40 (controls) an equal volume of physiological saline wa...
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Methods This study is a preplanned retrospective analysis of a large database created by Japan SEPTIC DIC study conducted in 41 ICUs. This study investigated associations between sepsis-related coagulopathy, anticoagulation therapies, and clinical outcomes of 3195 adult patients with severe sepsis and septic shock admitted to ICUs in Japan from January 2011 through December 2013. To estimate as...
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graphic deterioration, in the patient and others affected by aerosols of contaminated water in other factories2 3 no radiographic changes were evident after several years' exposure, and no functional abnormalities persisted when away from work. Furthermore, the symptoms were prominent in the early part of the week, improving while continuing at work, but recurring on return to work after an abs...
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ژورنال
عنوان ژورنال: New England Journal of Medicine
سال: 2002
ISSN: 0028-4793,1533-4406
DOI: 10.1056/nejm200209263471316